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Title: Design Synthesis and Chemistry of Fused Heterocyclic Compounds With Evaluation of their Pharmacological Activities
Researcher: Kalyankar Balasaheb Diliprao
Guide(s): Vartale S. P.
Keywords: Physical Sciences,Chemistry,Chemistry Medicinal
University: Swami Ramanand Teerth Marathwada University
Completed Date: 12/01/2018
Abstract: Section-A: Antioxidant activity. Antioxidats are those compounds which slows down the rate at which something decays because of oxidation. Antioxidant compounds are capable to either delay or inhibit the oxidation processes which occur under the influence of atmospheric oxygen or reactive oxygen species. Antioxidants are responsible for the defense mechanism of the organism against the pathologies associated to the attack of free radicals. Herein, we report the antioxidant activity of some newly synthesized compounds. Antioxidant activity was measured by DPPH and OH free radical model. The effectiveness of antioxidant potential was determined in terms of percent DPPH and OH radical scavenging assay. The DPPH radical scavenging assay has been used for preliminary screening of the samples for antioxidant activity. The proton radical scavenging action is known as an important mechanism of antioxidants. newline newlineSection-B: Antimicrobial activity. The newly synthesized compounds like benzothiazolo pyrimido pyrimidine, pyrazolo pyrimidine, pyrimido pyrimidine, benzothiazolo pyrimido thiazine, pyrazolo thiazine, benzothiazolo pyrazolo pyrimidine and pyrazolo pyrazoles were evaluated for their antimicrobial activity against different bacteria. The antimicrobial activity was done by disc diffusion method. Considerable antimicrobial potential was observed by tested compounds. newline
Pagination: 174p
Appears in Departments:School of Chemical Sciences

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02_certicate.pdf298.16 kBAdobe PDFView/Open
03_abstract.pdf522.95 kBAdobe PDFView/Open
04_declaration.pdf41.46 kBAdobe PDFView/Open
05_acknowldgement.pdf51.99 kBAdobe PDFView/Open
06_content.pdf255.82 kBAdobe PDFView/Open
07_list_of_table.pdf90.24 kBAdobe PDFView/Open
08_abbreviation.pdf228.23 kBAdobe PDFView/Open
09_chapter 1.pdf531.31 kBAdobe PDFView/Open
10_chapter 2.pdf1.99 MBAdobe PDFView/Open
11_chapter 3.pdf1.31 MBAdobe PDFView/Open
12_chapter 4.pdf1.97 MBAdobe PDFView/Open
13_chapter 5.pdf1.94 MBAdobe PDFView/Open
14_chapter 6.pdf387.16 kBAdobe PDFView/Open
15_conclusion.pdf304.09 kBAdobe PDFView/Open
16_bibliography.pdf282.13 kBAdobe PDFView/Open

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