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Title: Synthesis characterization and biological evaluation of Pyrazole Thiazole and Pyridine derivatives
Researcher: Yogi, Prabhunath
Guide(s): Joshi, Ajit
Keywords: derivatives
Pyrazole, Thiazole and Pyridine
Synthesis characterization and biological evaluation
University: Mewar University
Completed Date: 2017
Abstract: In our research we selected the topic of heterocyclic chemistry because more than 80% medicine and life protective substance made up from this part. In heterocyclic chemistry we selected only Pyrazole, Thiazole and Pyridine nucleus for synthesis of novel derivatives by conventional method because Pyrazole, Thiazole and Pyridine molecules have a broad spectrum of pharmacological evaluation such as antimicrobial activity, anti-inflammatory, herbicides, fungicides, analgesics, antiviral, antihypertensive, anticancer, osteogenic activities and treatment of CNS disorders. Conventional method widely used and applicable for production level at plant so our work carried out by only this process. newlinePresent research work carried out by well known named reaction like Vilsmeier Haack reaction, Hantzsch thiazole synthesis, multi component reaction etc. Total 38 novel compounds achived in good yield. The selected nucleuses were screened for their biological evaluation named antibacterial and antifungal activity via cup and well method. Some of the compounds exhibit moderate and good to strong activity against both microbial strains compared with standard drugs Ciprofloxacine and Flucanazole. The overall result is that synthesized compounds have great industrial importance and will become good antibacterial and antifungal agents in future newline
Pagination: XVIII, 183 P
Appears in Departments:Department of Chemistry

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02_dedication.pdf157.78 kBAdobe PDFView/Open
03_undertaking.pdf101.13 kBAdobe PDFView/Open
04_declaration.pdf56.71 kBAdobe PDFView/Open
05_certificates.pdf62.27 kBAdobe PDFView/Open
06_acknowledgement.pdf66.45 kBAdobe PDFView/Open
07_abstract.pdf82.41 kBAdobe PDFView/Open
08_contents.pdf15.56 kBAdobe PDFView/Open
09_tables & figures.pdf12.96 kBAdobe PDFView/Open
10_abbreviations.pdf11.07 kBAdobe PDFView/Open
11_preface.pdf112.21 kBAdobe PDFView/Open
12_chapter 1.pdf278.45 kBAdobe PDFView/Open
13_chapter 2.pdf2.3 MBAdobe PDFView/Open
14_chapter 3.pdf2.9 MBAdobe PDFView/Open
15_chapter 4.pdf1.35 MBAdobe PDFView/Open
16_chapter 5.pdf147.08 kBAdobe PDFView/Open
17_references.pdf238.12 kBAdobe PDFView/Open
18_publications.pdf74.59 kBAdobe PDFView/Open
19_biography.pdf205.82 kBAdobe PDFView/Open

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